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NORDBIOTIC™ PlasticFreeGut

From global pollution to your gut

Microplastics (MPs < 1 μm – 5 mm) and nanoplastics (NPs < 1 μm) are now found in drinking water, indoor air, seafood, rice, salt, and dairy products. Leading publications (BBC Future 2025, the World Economic Forum 2025, Stanford Medicine 2025) report that microplastics are no longer just an environmental concern – they accumulate inside the human body. Scientific studies have detected microplastics in:

Human stool

Human blood (Leslie et al., 2022)

Lung and liver tissue

Placenta (Ragusa et al., 2021) 

How microplastic gets to human body

When microplastics become a biological stressor 

Microbiome disruption

Microplastics alter gut microbial composition, reduce beneficial species, and promote dysbiosis. ( Jin et al., 2021)

Gut barrier damage

Microplastics impair tight junction proteins such as Occludin and ZO-1, contributing to increased intestinal permeability “leaky gut”. (ScienceDirect 2024; Stanford Medicine 2025)

Oxidative stress and inflammation

Microplastics generate reactive oxygen species and inflammatory signaling. (Yong et al., 2020)

Why the gut and bacteria are our first line of defence

The gastrointestinal tract is the primary entry point for ingested microplastics. 
This makes the microbiome – mucosal interface a uniquely powerful place to act. Specific probiotic strains can:

support natural elimination of bound particles through normal digestive transit

bind microplastic-like particles through hydrophobic and EPS structures

produce metabolites that help counteract oxidative stress

remain close to the mucosal layer (adhesion)

Internal research (Institute of Biochemistry and Biophysics, Polish 
Academy of Sciences, 2025) confirms that some strains show strong binding affinity to model microplastic particles 
(1 μm polystyrene beads), while others demonstrate potent antioxidant activity.

A multi-mechanism microbiome concept:
Bind - Buffer - Protect 

PlasticFreeGut integrates three strains with complementary activities that form a functional biological layer inside the gut.

The PlasticFreeGut
Strain Triad 

Bifidobacterium lactis NORDBIOTIC™ BI040 — Primary Microplastic Binder & Interface Strain

Bifidobacterium infantis NORDBIOTIC™ BSI050 
— Deep-Gut Microplastic Binder

Streptococcus thermophilus NORDBIOTIC™ ST250 — Antioxidant Shield & Supportive Binder

Bifidobacterium lactis NORDBIOTIC™ BI040 with 2 μm microspheres – large fluorescent beads attached to bacterial clusters 

Streptococcus thermophilus NORDBIOTIC™ ST250 with 1 μm microspheres – strong/moderate surface association 

Backed by scientific research

PlasticFreeGut is supported by in-vitro testing by the Institute of Biochemistry and Biophysics, Polish Academy of Sciences (IBB PAS), evaluating:

This aligns with emerging global research documenting microplastics in human biological tissues, dysbiosis, epithelial damage, and oxidative stress.

For nutraceutical and functional food brands 

PlasticFreeGut enables next-generation gut health innovation. Available for capsules, powders, sachets, fermented foods, and co-branded applications.

For more information and inquiries

Contact us at: hello@nordicbiotic.com